Forschungsartikel

Seggewiß N., H. V. Kruse, R. Weilandt, E. Domsgen, A. Dotzauer, and D. Paulmann. 2016. Cellular localization and effects of ectopically expressed hepatitis A virus proteins 2B, 2C, 3A and their intermediates 2BC, 3AB and 3ABC. Arch. Virol., 161(4): 851-865, DOI 10.1007/s00705-015-2723-5.

Seggewiß N., D. Paulmann, and A. Dotzauer. 2016. Lysosomes serve as platform for hepatitis A virus particle maturation and nonlytic release. Arch. Virol., 161(1): 43-52, DOI 10.1007/s00705-015-2634-5.

Drexler J. F., V. M. Corman, A. N. Lukashev, J. M. A. van den Brand, A. Gmyl, S. Brünink, A. Rasche, N. Seggewiß, H. Feng, L. M. Leijten, P. Vallo, T. Kuiken, A. Dotzauer, R. G. Ulrich, S. M. Lemon, C. Drosten, and the Hepatovirus Ecology Consortium. 2015. Evolutionary origins of hepatitis A virus in small mammals. Proc. Natl. Acad. Sci. USA, DOI 10.1073/pnas.1516992112.

Weilandt R., D. Paulmann, K. Schlottau, A. Vallbracht, and A. Dotzauer. 2014. Mutational modifications of hepatitis A virus proteins 2B and 2C described for cell culture-adapted and attenuated virus are present in wild-type populations. Arch. Virol., 159: 2699-2704, DOI 10.1007/s00705-014-2103-6.

Paulmann D., S. Bortmann, F. Grimm, I. Berk, L. Kraemer, A. Vallbracht, and A. Dotzauer. 2014. NF-kB activation induced by hepatitis A virus and Newcastle disease virus occurs by different pathways depending on the structural pattern of viral nucleic acids. Arch. Virol., 159: 1723-1733, DOI 10.1007/s00705-014-1993-7.

Meder F., J. Wehling, A. Fink, B. Piel, K. Li, K. Frank, A. Rosenauer, L. Treccani, S. Koeppen, A. Dotzauer, and K. Rezwan. 2013. The role of surface functionalization of colloidal alumina particles on their controlled interactions with viruses. Biomaterials, 34: 4203-4213.

Prabhune M., G. Belge, A. Dotzauer, J. Bullerdiek, and M. Radmacher. 2012. Comparison of mechanical properties of normal and malignant cells. Micron, 43: 1267-1272.

Dotzauer A., A. Heitmann, T. Laue, L. Kraemer, K. Schwabe, D. Paulmann, B. Flehmig, and A. Vallbracht. 2012. The role of immunoglobulin A in prolonged and relapsing hepatitis A virus infections. J. Gen. Virol., 93: 754-760.

Paulmann, D., T. Magulski, R. Schwarz, L. Heitmann, B. Flehmig, A. Vallbracht, and A. Dotzauer. 2008. Hepatitis A virus protein 2B suppresses IFN-b gene transcription by interfering with IRF-3 activation. J. Gen. Virol., 89: 1593-1604.

Dotzauer, A., M. Brenner, U. Gebhardt, and A. Vallbracht. 2005. IgA-coated particles of hepatitis A virus are translocalized antivectorially from the apical to the basolateral site of polarized epithelial cells via the polymeric immunoglobulin receptor. J. Gen. Virol., 86: 2747-2751.

Fensterl, V., D. Grotheer, I. Berk, S. Schlemminger, A. Vallbracht, and A. Dotzauer. 2005. Hepatitis A virus suppresses RIG-I-mediated IRF-3 activation to block induction of beta interferon. J. Virol., 79: 10968-10977.

Heitmann, A., T. Laue, V. Schottstedt, A. Dotzauer, and L Pichl. 2005. Occurrence of hepatitis A virus genotype III in Germany requires the adaptation of commercially available diagnostic test systems. Transfusion, 45 (7): 1097-1105.

Normann, A., C. Jung, A. Vallbracht, and B. Flehmig. 2003. Time Course of Hepatitis A Viremia and Viral Load in the Blood of Human Hepatitis A Patients. J Med Virol 72: 10-16.

Brack, K., I. Berk, T. Magulski, J. Lederer, A. Dotzauer, and A. Vallbracht. 2002. Hepatitis A virus inhibits cellular anti-viral defense mechanisms induced by double-stranded RNA. J. Virol., 76: 11920-11930.

Wünschmann S, B. Becker, and A. Vallbracht. 2002. Hepatitis A Virus suppresses Monocyte-to-Macrophage Maturation in vitro. J Virol 76, 4350-4356.

Hornei, B., R. Kämmerer, P. Moubayed, W. Frings, V. Gauss-Müller, and A. Dotzauer. 2001. Experimental hepatitis A virus infection in guinea pigs. J. Med. Virol., 64: 402-409.

Frings, W., and A. Dotzauer. 2001. Adaptation of primate cell-adapted hepatitis A virus strain HM175 to growth in guinea pig cells is independent from mutations in the 5’ nontranslated region. J. Gen. Virol., 82: 597-602.

Dotzauer, A., U. Gebhardt, K. Bieback, U. Göttke, A. Kracke, J. Mages, S. M. Lemon, and A. Vallbracht. 2000. Hepatitis A virus-specific immunoglobulin A mediates infection of hepatocytes with hepatitis A virus via the asialoglycoprotein receptor. J. Virol., 74: 10950-10957.

Schmitz, G., and A. Dotzauer. 1998. Proof of hepatitis A virus negative-sene RNA by RNA/DNA-hybrid detection: A method for specific detection of both viral negative- and positive-strand RNA species. Nucleic Acids Res., 26: 5230-5232.

Brack, K., W. Frings, A. Dotzauer, and A. Vallbracht. 1998. A cytopathogenic, apoptosis-inducing variant of hepatitis A virus. J. Virol., 72: 3370-3376.

Dotzauer, A., A. Vallbracht, and G. M. Keil. 1995. The proposed gene for VP1 of HAV encodes for a larger protein than that observed in HAV-infected cells and virions. Virology, 213: 671-675.

Dotzauer, A., S. M. Feinstone, and G. Kaplan. 1994. Susceptibility of nonprimate cell lines to hepatitis A virus infection. J. Virol., 68: 6064-6068.

Graff, J., A. Dotzauer, J. R. Ticehurst, A. Vallbracht, and B. Flehmig. 1993. Detection of hepatitis A virus in sludge by blot hybridization and cell culture technique. In Wiener Mitteilungen zu Contamination of the environment by viruses and methods of control, Band 112: 1-4.

Vallbracht A., J. Löhler, J. Gossmann, T. Glück, D. Petersen, H.J. Gerth, M. Gencic, and K. Dörries. 1993. Disseminated BK type polyomavirus infection in an AIDS patient associated with central nervous system disease. Am J Path 143, 29-39.

Einsele H., G. Ehninger, M. Steidle, I. Fischer, S. Bihler, F. Gerneth, A. Vallbracht, H. Schmidt, H.D. Waller, and C.A. Müller. 1993. Lymphocytopenia as an unfavourable prognostic factor in patients with CMV infection after bone marrow transplantation. Blood 82, 1672-1678.

Busch F.W., A. Kunst, B. Flehmig, H.G. Mergenthaler, G. Pawelec, and A. Vallbracht. 1992. Myelopoiesis in vitro is suppressed by hepatitis A virus. Ann Hematol 64, 132-136.

Einsele H., R. Steidle, A. Vallbracht, G. Saal, G. Ehninger, and C.A. Müller. 1991. Early occurence of human cytomegalovirus infection after bone marrow transplantation as demonstrated by the polymerase chain reaction technique. Blood 77, 1104-1110.

Einsele H., G. Ehninger, M. Steidle, A. Vallbracht, M. Müller, H. Schmidt, J.G. Saal, H.D. Waller, and C.A. Müller. 1991. Polymerase chain reaction to evaluate antiviral therapy for cytomegalovirus disease. Lancet 338, 1170-1172.

Fleischer B., and A. Vallbracht. 1991. Demonstration of virus-specific cytotoxic T lymphocytes in liver tissue in hepatitis A - a model for immunopathological reactions. Behring Inst Mitt 89, 226-230.

Martin R., A. Vallbracht, and H.W. Kreth. 1991. Interferon-gamma secretion by in vivo activated cytotoxic T lymphocytes from the blood and cerebrospinal fluid during mumps miningitis. J Neuroimmunol 33, 191-198.

Einsele H., A. Vallbracht, and C.A. Müller.1990. Comparison of different techniques for detection of cytomegalovirus infection following bone marrow transplantation. Eur J Clin Microbiol Infect Dis 9, 595-600.

Fleischer B., S. Fleischer, K. Maier, K.H. Wiedmann, M. Sacher, H. Thaler, and A. Vallbracht. 1990. Clonal analysis of infiltrating T lymphocytes in liver tissue in viral hepatitis A. Immunology 69, 14-19.

Liebich, H. M., and A. Dotzauer. 1989. Quantitative determination of oxocarboxylic and hydroxycarboxylic acids in normal individuals and ketoacidotic patients. Journal of High Resolution Chromatography, 12: 160-163.

Liebich, H. M., A. Dotzauer, and B. Tetschner. 1989. Gas chromatographic determination of oxo- and hydroxycarboxylic acids in serum and urine of diabetic and normal subjects. J. Chromatogr., 468: 157-165.