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Wissenschaftliche_r Mitarbeiter_in

The Institute of Biophysics of the University of Bremen (Faculty 1 of Physics & Electrical Engineering)
as a member of the

                 Marie Sklodowska-Curie Action - European Innovative Training Network
                Biomechanics in health and disease: advanced physical tools for innovative early
                diagnosis (Phys2BioMed)


invites applications for the following academic position – under the condition of job release -

                            1 full Early Stage Researcher/PhD Position
                            Salary level TV-L 13  / full-time position

The earliest starting date is 1st, March 2019 and the position is limited to a term of  3 years.

The employment is fixed-term and governed by the Act of Academic Fixed-Term Contract,
§2 I (Wissenschaftszeitvertragsgesetz – WissZeitVG). Therefore, candidates may only be considered#
for appointment if they still have the respective qualification periods available in accordance
with § 2 (1) WissZeitVG.

The Phys2BioMed network:
The network “Biomechanics in health and disease: advanced physical tools for innovative early diagnosis”
(Phys2BioMed) will involve sixteen partners (eleven beneficiaries hiring young researchers and five partner
organizations supporting training and research), merging diverse competences at the European level, from different
fields like nanoscience and nanotechnology, physics, biology, and medicine. Phys2BioMed will offer excellent
interdisciplinary and cross-sectoral training to a team of motivated early stage researchers (ESRs) on the
application of cutting-edge physical tools for the mechanical phenotyping of cells and tissues of clinical
relevance, aiming at developing novel early-diagnostic tools.
A key element of the project is the peer-to-peer
collaboration of research academic institutions with industries and world-leading medical and clinical centers; they
will highlight unmet clinical needs, and actively cooperate with academic colleagues for developing novel
diagnostic strategies. ESRs will be trained-through-research by world-leading junior and senior PIs, and will
benefit of lecture courses, dedicated international schools and workshops, and topical conferences. Secondments
to other nodes of the network will represent the main and more effective channel of dissemination and
cross-fertilization of competences, ideas, and knowledge within the network.
Phys2BioMed will provide scientific and technological outcomes on biomechanics, and the mechanical determinants
of diseases. Technology-wise, it willefine standardized procedures for nanomechanical measurements, and the definition
of the main features of new generation instrumentation optimized for the mechanical phenotyping of clinical specimens.
In the longer-term, Phys2BioMed will provide the platform and know-how to build a data bank of mechanical fingerprints
of diseases, setting the ground for the development of effective early-diagnostic tools.

Required qualifications:
We are looking for excellent and highly motivated candidates with a master degree in physics, biology, chemistry,
bioengineering, medicine or related subjects
, and strong interest and experience in cellular biology, biophysics,
bioengineering, biomedicine, physiology, and related disciplines, including advanced microscopy, statistics and
computer science. We expect dedication and enthusiasm for experimental research, combined with openness and curiosity,
and the ability and willingness to team working in an interdisciplinary environment.

For this position we are looking for a candidate being trained in biophysics or related fields to develop variants
of AFM allowing to measure the creep response of cells and tissues. Beyond instrumentation, this also requires the
development of models for the viscoelastic behaviour of cells and tissues and data analysis tools to obtain values
for storage and loss moduli. The methods will be tested on cancer cell lines, which have been shown to exhibit a
well-defined mechanical fingerprint. The elaborated methodology of creep measurements and theoretical models will
be applied to evaluate viscoelastic phenotype in cancer tissues.

The ESRs’ projects will be part of a vibrant and stimulating international and inter-sectorial collaboration.
The research training provided will comprise a broad portfolio of technical and transferable skills on local and
network level. Strong participation of non-academic partners, including fully private companies and medical
institutions, and the interaction of academic and non-academic partners, are meant to foster career opportunities,
in particular to drive the emerging role of technically and scientifically skilled workers in the biomedical
environment. Several secondments (short term training visits) at the laboratories of partners of the network
are planned.


The candidate recruited in the Phys2BioMed project must be in the first four years from the date when the candidat
obtained the degree entitling him or her to embark on a doctorate (e.g. master degree). No doctoral degree has been
awarded during these four years. The candidate must not have resided or carried out her/his main activity
(work, studies, etc.) in Germany for more than 12 months in the 3 years immediately prior to the recruitment date.
Compulsory national service, short stays such as holidays, and time spent as part of a procedure for obtaining
refugee status under the Geneva Convention are not taken into account. The candidate must work exclusively for
the project during the employment contract. The candidate must fulfil the conditions to be admitted in the PhD
programme indicated in the job vacancy. Good proficiency in written and spoken English is required (level B2).
Tuition fees will be covered by the fellowship. These conditions must be fulfilled at the starting date of the
contract. The selected candidate will be employed full-time as an Early Stage Researcher. The position is limited
to a term of up to 3 years and funded by the European Commission with a salary 100% TVL-13 linked to
the German system.

As the University of Bremen intends to increase the proportion of female employees in science, women are
particularly encouraged to apply.

In case of equal personal aptitudes and qualification, disabled persons will be given priority.


For further information, please contact Prof. Dr.Manfred Radmacher, mr@biophysik.uni-bremen.de,
Tel. – 0049 421 218 62280

Please send your application (motivation letter, detailed CV, certificates, list of MSc courses and grades,
copy of the master thesis, reference letter etc)  under the job ID A323/18  before Febraury 21, 2019 to:

University of Bremen
Faculty 1 of Physics & Electrical Engineering
Institute of Biophysics
Secretary of Prof. Manfred Radmacher
Mrs. Janka Heits
Otto-Hahn-Allee 1
28359 Bremen

or electronically and combined into a single PDF file to jh@biophysik.uni-bremen.de

Please do not send any originals or folders, as we cannot return any applications for cist reasons,

Erstellt am 27.12.18 von Rebekka Rosner