60 https://www.uni-bremen.de/en/molgen/research/mitochondria University Bremen, Faculty 2, Biology, Chemistry, Research, Molecular Genetics, Mitochondria, Codes, Communication, Prof. Rita Groß-Hardt en University of Bremen Mon, 18 May 2026 14:40:50 +0200 Mon, 18 May 2026 14:40:50 +0200 University of Bremen content-436469 Fri, 06 Mar 2026 09:32:06 +0100 https://www.uni-bremen.de/en/molgen/research/mitochondria#c436469 <p>Multicellular organisms are energized by numerous often highly dynamic cellular organelles, termed mitochondria.</p> <p>On a weight basis, a single mitochondrion converts "between 10,000 and 50,000 times more energy per second than the sun." (1)</p> <p>Apart from their impressive role in energy production, mitochondria are involved in various cellular processes including Ca2+ signaling, redox homeostasis and the regulation of programmed cell death (2).</p> Content content-436464 Fri, 06 Mar 2026 09:32:06 +0100 https://www.uni-bremen.de/en/molgen/research/mitochondria#c436464 <ol> <li class="EndNoteBibliography">Schatz, G. The Magic Garden. <em>Annual Review of Biochemistry</em><strong>  </strong>76, 673-678 (2007).</li> <li>A. V. Kuznetsov, R. Margreiter, Heterogeneity of mitochondria and mitochondrial function within cells as another level of mitochondrial complexity. Int J Mol Sci 10, 1911-1929 (2009).</li> <li>R. N. Lightowlers, R. W. Taylor, D. M. Turnbull, Mutations causing mitochondrial disease: What is new and what challenges remain? Science 349, 1494-1499 (2015).</li> <li>S. B. Ong et al., Inhibiting mitochondrial fission protects the heart against ischemia/reperfusion injury. Circulation 121, 2012-2022 (2010).</li> <li>P. H. Reddy et al., Dynamin-related protein 1 and mitochondrial fragmentation in neurodegenerative diseases. Brain Res Rev 67, 103-118 (2011).</li> <li>M. Williams, M. C. Caino, Mitochondrial Dynamics in Type 2 Diabetes and Cancer. Front Endocrinol (Lausanne) 9, 211 (2018).</li> <li class="EndNoteBibliography">Y. Yoon, C. A. Galloway, B. S. Jhun, T. Yu, Mitochondrial dynamics in diabetes.  Antioxid Redox Signal 14, 439-457 (2011).</li> <li class="EndNoteBibliography">L. Melhuish Beaupre, Gregory M. Brown (2022) Mitochondria’s role in sleep: Novel insights from sleep deprivation and restriction studies, The World Journal of Biological Psychiatry, 23:1, 1-13, DOI: 10.1080/15622975.2021.1907723</li> </ol> Content