Publikationen

Scholarly book chapters

Weinbauer MG, Großkurth A, Kerros ME, Harder T, DuBow M, Gattuso JP, Maier C (2019) Diversity of Bacteria Associated with the Cold Water Corals Lophelia pertusa and Madrepora oculata. In: Orejas C., Jiménez C. (eds) Mediterranean Cold-Water Corals: Past, Present and Future. Coral Reefs of the World, vol 9. Springer

Harder T, Tebben J, Möller M, Schupp AP (2018) Chemical ecology of marine invertebrate larval settlement. In: Paul V; Becerro MA, Puglisi-Weening M (eds.) Chemical Ecology. The ecological impacts of marine natural products. Taylor and Francis, Boca Raton.

Harder T, Rice S, Dobretsov S, Thomas T, Carré-Mlouka A, Kjelleberg S, Steinberg P, McDougald D. Bacterial communication systems. In: Kornprobst JM, La Barre S (eds): Outstanding Marine Molecules and New Trends in Analytical Methods. Wiley-VCH, 2014 Weinheim, Chapter 7, pp. 173-187

Campbell AH, Verges A, Harder T, Steinberg PD. Causes and ecological consequences of a climate-mediated disease. In: Lunney D & Hutchings P (eds): Wildlife and Climate Change: toward robust conservation strategies for Australian fauna. Royal Zoological Society of New South Wales, 2012 Mosman, NSW, Australia, pp. 52-58

Harder T. Marine epibiosis: Concepts, ecological consequences and host defence. In: Flemming HC, Venkatesan R, Murthy SP, Cooksey, K (eds): Marine and Industrial Biofouling. 2008 Springer Heidelberg New York, Chapter 12, vol. 4, pp. 219-232

Harder T, Yee L. Bacterial bioadhesion. In Hellio C, Yebra DMY (eds) Advances in marine antifouling coating and technologies. 2008 Woodhead Publishing, Cambridge, Chapter 5, pp. 113-125

Harder T. Isolation and elucidation of a sex pheromone of the marine polychaete Platynereis dumerilii (Annelida, Polychaeta), in Edition Wissenschaft, Reihe Chemie, 1997 Tectum Verlag Marburg (ISBN 3-89608-099-7), Vol. 73, pp 1-146

Journal publications

Alison Butler, Tilmann Harder, Alexis D Ostrowski, Carl J Carrano (2021) Photoactive siderophores: Structure, function and biology. J Inorg Biochem, 111457

David A Aromokeye, Oluwatobi E Oni, Jan Tebben, Xiuran Yin, Tim Richter-Heitmann, Jenny Wendt, Rolf Nimzyk, Sten Littmann, Daniela Tienken, Ajinkya C Kulkarni, Susann Henkel, Kai-Uwe Hinrichs, Marcus Elvert, Tilmann Harder, Sabine Kasten, Michael W Friedrich (2021) Crystalline iron oxides stimulate methanogenic benzoate degradation in marine sediment-derived enrichment cultures.The ISME journal 15 (4), 965-980

Nachshon Siboni, David Abrego, Eneour Puill-Stephan, William L King, David G Bourne, Jean-Baptiste Raina, Justin R Seymour, Tilmann Harder (2020).Crustose coralline algae that promote coral larval settlement harbor distinct surface bacterial communities. Coral Reefs 39 (6), 1703-1713

Christian Zurhelle, Tilmann Harder, Urban Tillmann, Jan Tebben (2020) In Silico Modeling of Spirolides and Gymnodimines: Determination of S Configuration at Butenolide Ring Carbon C-4.Toxins 12 (11), 685

Angel Borja, Jesper H Andersen, Christos D Arvanitidis, Alberto Basset, Lene Buhl-Mortensen, Susana Carvalho, Katherine A Dafforn, Michelle J Devlin, Elva G Escobar-Briones, Christian Grenz, Tilmann Harder, Stelios Katsanevakis, Dongyan Liu, Anna Metaxas, Xosé Anxelu G Morán, Alice Newton, Chiara Piroddi, Xavier Pochon, Ana M Queirós, Paul VR Snelgrove, Cosimo Solidoro, Michael A St John, Heliana Teixeira. (2020) Past and future grand challenges in marine ecosystem ecology. Front Mar Sci 7, 362 (doi.org/10.3389/fmars.2020.00362)

Egbers P, Harder T, Koch B, Tebben J (2020) Siderophore purification with titanium dioxide nanoparticle solid phase extraction. Analyst 145, 7303-7311.

Mönnich J, Tebben J, Bergemann J, Case R, Wohlrab S, Harder T. (2020) Niche-based assembly of bacterial consortia on the diatom Thalassiosira rotula is stable and reproducible. ISME J 14:1614-1625

Becker B, Tebben J, Coffinet S, Wiltshire K, Iversen MH, Harder T, Hinrichs KU, Hehemann JH (2020) Laminarin is a major molecule in the marine carbon cycle. PNAS 117:6599-6

2019 - 2013

M Saha, E Berdalet, Y Carotenuto, P Fink, T Harder, U John,  F Not, G Pohnert, P Potin, E Selander, W Vyverman, T Wichard, V Zupo, M Steinke (2019) Using chemical language to shape future marine health. Front Ecol Env 17:530-37

Dittami SM, Arboleda E, Auguet JC, Bigalke A, Briand E, Cárdenas P, Cardini U, Decelle J, Engelen A, Eveillard D, Gachon C, Griffiths S, Harder T, Kayal E, Kazamia E, Lallier FH, M Marzinelli E, Morganti T, Núñez Pons L, Prado S, Pintado J, Saha M, Selosse MA, Skillings D, Stock W, Sunagawa S, Toulza E, Vorobev A, Leblanc C, Fabrice Not (2019) A community perspective on the concept of marine holobionts: state-of-the art, challenges, and future directions. PeerJ e27519v1

Wietz M, Lau SCK, Harder T (2019) Socio-Ecology of Microbes in a Changing Ocean. Front Mar Sci 6: 190

Zurhelle C, Nieva J, Tillmann U, Harder T, Krock B, Tebben J (2018) Identification of novel gymnodimines and spirolides from the marine dinoflagellate Alexandrium ostenfeldii. Mar Drugs 16:446

Tareq FS, Hasan CM, Rahman MM, Hanafi MM, Ciacchi LC, Michaelis M, Harder T, Tebben J, Islam MD, Spiteller P (2018) Anti-stapylococcal calopins from fruiting bodies of Caloboletus radicans. J Nat Prod 81:400-404

Tebben J, Motti CA, Siboni N, Tapiolas DM, Negri AP, Schupp PJ, Kitamura M, Hatta M, Steinberg PD, Harder T (2015) Chemical mediation of coral larval settlement by crustose coralline algae. Sci Rep 5:10803

Nielsen S, Harder T, Steinberg PD (2015) Sea urchin larvae decipher the epiphytic bacterial community composition when selecting sites for attachment and metamorphosis. FEMS Microbiology Ecology 91: doi: 10.1093/femsec/fiu011

Tebben J, Motti C, Tapiolas D, Thomas-Hall P, Harder T (2014) A Coralline Algal-associated Bacterium, Pseudoalteromonas sp. strain J010, Yields Five New Korormicins and a Bromopyrrole. Mar Drugs 12:2802-2815

Siboni N, Abrego D, Motti C, Tebben J, Harder T (2014) Gene expression patterns during the early phase of chemically induced larval metamorphosis and settlement of the coral Acropora milleporaPLoS One 9(3):e91082

Tebben J, Guest J, Sin T, Steinberg P, Harder T (2014) Corals like it waxed: paraffin-based antifouling technology enhances coral spat survival. PLoS One 9(1): e87545

Sebesvari Z, Neumann R, Brinkhoff T, Harder T (2013) Single-species bacteria in sediments induce larval settlement of the infaunal polychaetes Polydora cornuta and Streblospio benedicti. Mar Biol 160:1259-1270

Lachnit T, Fischer M, Künzel S, Baines JF, Harder T (2013) Compounds associated with algal surfaces mediate epiphytic colonization of the marine macroalga Fucus vesiculosusFEMS Microbiol Ecol 84:411-420

Egan S, Harder T, Burke C, Steinberg P, Kjelleberg S, Thomas T (2013) The seaweed holobiont: understanding bacteria-seaweed interactions.  FEMS Microbiol Reviews 37:462-476

2012 - 2009

Enge S, Nylund GM, Harder T, Pavia H (2012) An exotic chemical weapon explains low herbivore damage in an invasive alga. Ecology 93:2736-2745

Harder T, Campbell AH, Egan S, Steinberg P (2012) Chemical mediation of ternary interactions between marine holobionts and their environment as exemplified by the red alga Delisea pulchraJ Chem Ecol: 38:442-450

Siboni N, Abrego D, Seneca F, Motti CA, Andreakis N, Tebben J, Blackall LL, Harder T (2012) Using bacterial extract along with differential gene expression in Acropora millepora larvae to decouple the processes of attachment and metamorphosis. PLoS One 7(5): e37774

Bernbom N, Ng N, Kjelleberg S, Harder T, Gram L (2011) Marine bacteria isolated from Danish coastal waters show antifouling activity against the marine fouling bacterium Pseudoalteromonas S91 and zoospores of the green alga Ulva australis independent of bacteriocidal activity. Appl Env Microbiol 77:8557-85567

Steinberg P, Rice S, Campbell A, McDougald D, Harder T (2011) Interfaces between bacterial and eukaryotic “neuroecology”. Int Comp Biol 51:794-806

Penesyan A, Tebben J, Lee M, Thomas T, Kjelleberg S, Harder T, Egan S (2011) Identification of the antibacterial compound produced by the marine epiphytic bacterium Pseudovibrio sp. D323 and related sponge-associated bacteria. Mar Drugs 9:1391-1402

Campbell AC, Harder T, Nielsen S, Kjelleberg S, Steinberg P (2011) Climate change and disease: bleaching of a chemically defended seaweed. Global Change Biology 17:2958-2970

Tebben J, Tapiolas DM, Motti CA, Abrego D, Negri AP, Blackall LL, Steinberg PD, Harder T (2011) Induction of larval metamorphosis of the coral Acropora millepora by tetrabromopyrrole isolated from a Pseudoalteromonas bacterium. PLoS One  6(4): e19082

Rittschof D, Orihuela B, Harder T, Stafslien S, Chisholm B, Dickinson GH (2011) Compounds from silicones alter enzyme activity in barnacle glue and model enzymes. PLoS One 6: e16487

Lachnit T, Meske D, Wahl M, Harder T, Schmitz R (2011) Epibacterial community patterns on marine macroalgae are host-specific but temporally variable. Env Microbiol 13:655-665

Lachnit T, Wahl M, Harder T (2010) Isolated thallus-associated compounds of the macroalga Fucus vesiculosus mediate bacterial surface colonization in the field similar to that on the natural alga. Biofouling 26: 247-255

Schmidt G, Rittschof D, Lutostanski K, Batchelder A, Harder T (2009) 3-Decanol in the haemolymph of the hermit crab Clibanarius vittatus signals shell availability to conspecifics. J Exp Mar Biol Ecol 382: 47-53

2008 and earlier

Esser F, Winterberg M, Sebesvari Z, Harder T (2008) Effect of halogenated metabolites from infaunal polychaetes on larval settlement of the spionid polychaete Streblospio benedictiMar Ecol Prog Ser 355: 161-172

Dubber D, Harder T (2008) Extracts of Ceramium rubrumMastocarpus stellatus and Laminaria digitata inhibit growth of marine and fish pathogenic bacteria at ecologically realistic concentrations. Aquaculture 274: 196-200

Lam C, Grage A, Schulz D, Schulte A, Harder T (2008) Extracts of North Sea macroalgae reveal specific activity patterns against attachment and proliferation of benthic diatoms: a laboratory study. Biofouling 24: 59-66

Lam C, Stang A, Harder T (2008) Planktonic bacteria and fungi are selectively eliminated by exposure to marine macroalgae in close proximity. FEMS Microbiol Ecol 63: 283-291

Lam C, Harder T (2007) Marine macroalgae affect abundance and community richness of bacterioplankton in close proximity J Phycol 43:874-881

Dahms HU, Harder T, Qian PY (2007) Selective attraction and reproductive performance of a harpacticoid copepod in a response to biofilms. J Exp Mar Biol Ecol 341:228-338

Qian PY, Lau SCK, Dahms HU, Dobretsov S, Harder T (2007) Marine biofilms as mediators of colonization by marine macroorganisms: Implications for antifouling and aquaculture. Mar Biotech 9: 399-410

Sebesvari Z, Esser F, Harder T (2006) Sediment-associated cues for larval settlement of the inbenthic spionid polychaetes Polydora cornuta and Streblospio benedictiJ Exp Mar Biol Ecol 337:109-120

Dobretsov S, Dahms HU, Harder T, Qian PY (2006) Allelochemical defense of the macroalga Caulerpa racemosa against epibiosis: evidence of field and laboratory assays. Mar Ecol Prog Ser 318: 165-175

Kittelmann S, Harder T (2005) Species- and site-specific bacterial communities associated with four encrusting bryozoans from the Jade Germany). J Exp Mar Biol Ecol 327: 201-209

Lam C, Harder T, Qian PY (2005) Growth conditions of pennate diatoms affect quality and quantity of extracellular polymeric larval settlement cues. Mar Ecol Prog Ser  294: 109–116

Lam C, Harder, Qian PY (2005) Induction of larval settlement in the polychaete Hydroides elegans by extracellular polymers of benthic diatoms. Mar Ecol Prog Ser 286: 145-154

Dahms HU, Harder T, Qian PY (2004) Effect of meiofauna on macrofoauna recruitment: settlement inhibition of the polychaete Hydroides elegans by the harpacticoid copepod Tisbe japonicaJ Exp Mar Biol Ecol 311: 47-61

Harder T, Dobretsov S, Qian PY (2004) Waterborne, polar macromolecules act as algal antifoulants in the seeweed Ulva reticulataMar Ecol Prog Ser274: 131-141

Harder T, Lau SCK, Tam WY, Qian PY (2004) A bacterial culture-independent method to investigate chemically-mediated control of bacterial epibiosis in marine invertebrates by using TRFLP analysis and natural bacterial populations. FEMS Microb Ecol 47: 93-99

Thiyagarajan V, Harder T, Qian PY (2003) Effects of TAG/DNA ratio and age of cyprid on post-metamorphic growth and survival in the barnacle Balanus amphitrite. J Mar Biol Assoc UK 83: 83-88

Harder T, Lau SCK, Dobretsov S, Fang TK, Qian PY (2003) A distinctive epibiotic bacterial community on the soft coral Dendronephthya sp. and antibacterial activity of coral tissue extracts suggest a chemical mechanism against bacterial epibiosis. FEMS Microb Ecol 43: 337-347

Thiyagarajan V, Harder T, Qian PY (2003) Combined effect of temperature and salinity on larval development and attachment of the subtidal barnacle Balanus trigonus Darwin. J Exp Mar Biol Ecol 287: 223-236

Lau SCK, Harder T, Qian PY (2003) Induction of larval settlement in the serpulid polychaete Hydroides elegans (Haswell): Role of bacterial extracellular polymers. Biofouling 19: 197-204

Thiyagarajan V, Harder T, Qiu JW, Qian PY (2003) Energy content at metamorphosis and growth rate of the early juvenile barnacle Balanus amphitrite Darwin Mar Biol 143: 543-554

Lam C, Harder T, Qian PY (2003) Induction of larval settlement in the polychaete Hydroides elegans by surface-associated settlement cues of marine benthic diatoms. Mar Ecol Prog Ser 263: 83-92

Harder T, Lam C, Qian PY (2002) Induction of larval settlement of the polychaete Hydroides elegans (Haswell) by marine biofilms: An investigation of monospecific diatom films as settlement cues. Mar Ecol Prog Ser 229: 105-112

Thiyagarajan V, Harder T, Qian PY (2002) Effect of the physiological condition of cyprids and laboratory-mimicked seasonal conditions on the metamorphic success of Balanus amphitrite Darwin. J Exp Mar Biol Ecol 274: 65-74

Harder T, Lau SCK, Dahms HU, Qian PY (2002) Isolation of bacterial metabolites as natural inducers for larval settlement in the marine polychaete Hydroides elegans (Haswell). J Chem Ecol 28: 2009-2023

Thiyagarajan V, Harder T, Qian PY (2002) Relationship between cyprid energy reserves and metamorphosis in the barnacle Balanus amphitriteDarwin (Cirripedia; Thoracica). J Exp Mar Biol Ecol 280: 79-93

Harder T, Thiyagarajan V, Qian PY (2001) Effect of cyprid age on the settlement of Balanus amphitrite Darwin in response to natural biofilms. Biofouling 17: 211-219

Harder T, Thiyagarajan V, Qian PY (2001) Combined effect of cyprid age and lipid content on larval attachment and metamorphosis of Balanus amphitrite Darwin. Biofouling 17: 257-262

Harder T, Qian PY (2000) Waterborne compounds from the green seaweed Ulva reticulata as inhibitive cues for larval attachment and metamorphosis in the polychaete Hydroides elegans. Biofouling 16: 205-214

Beckmann M, Harder T, Qian PY (1999) Induction of larval attachment and metamorphosis in the serpulid polychaete Hydroides elegans by dissolved free amino acids: mode of action in laboratory bioassays. Mar Ecol Prog Ser 190: 167-178

Harder T, Qian PY (1999) Induction of larval attachment and metamorphosis in the serpulid polychaete Hydroides elegans by dissolved free amino acids: Isolation and identification. Mar Ecol Prog Ser 179: 259-271

Zeeck E, Harder T, Beckmann M. (1998) Inosine, L-glutamic acid and L-glutamine as components of a sex pheromone complex of the marine polychaete Nereis succinea (Annelida: Polychaeta). Chemoecology 8: 77-84

Zeeck E, Harder T, Beckmann M (1998) Uric acid - the sperm-release pheromone of the marine polychaete Platynereis dumerilii. J Chem Ecol 24: 13-22

Zeeck E, Harder T, Beckmann M, Müller CT (1996) Marine gamete-release pheromones. Nature 382: 214