The laboratory of virus research works on the pathogenesis (processes leading to disease) of viral infections and on the interactions between viruses and their host cells. The hepatitis A virus serves as a model (for a survey see Dotzauer, 2014, publications books), as it is suitable for the investigation of both general viral and virus specific principles and also for the investigation of the viral replication. Although vaccines are available, the hepatitis A virus infection is one of the most common infectious diseases, with clearly more than 10 million cases per year of which some take a very serious course. There is no specific therapy for this very heterogenous infectious disease, as important details of the virus/host interaction are not known. The research work is presented in publications and graduation theses.