MicroSys excursion to visit companies and check out prospective career options.
MicroSys company visits
Working with C. elegans
Bench work with the nematode C.elegans to study protein folding.
In the lab
Analysing qRT-PCR data.
The great mitochondrial bake off: from left to right: Olivia Masseck, Janine Kirstein, Kathrin Mädler and Rita Groß-Hardt.
The blueprint of life on our skin! DNA tattooing on Campus Day.
You cannot start early enough to become a scientist. Prof. Reinhold-Hurek shows school kids how to work in the lab.
Stem cell colony
Stem cell colony that expresses the correct marker OCT4 (in green). The chromatin is depicted in blue (DAPI staining).
Mario Waespy at the bench
master program BMB course studies (May 2022)File name: Poster_MSc_BMB_Studienverlauf_Mai22.pdfLast update: 23.05.2022
Who is who?
The laboratory of virus research works on the pathogenesis (processes leading to disease) of viral infections and on the interactions between viruses and their host cells. The hepatitis A virus serves as a model, as it is suitable for the investigation of both general viral and virus specific principles and also for the investigation of hepatocellular viral replication.
For more information: Virology
The Dringen neurobiochemistry group investigates basic metabolic processes in brain and the metabolic interactions that take place between different types of brain cells. Aim of our studies is to improve the knowledge on metabolic processes in brain and to elucidate the mechanisms involved in disturbances of brain metabolism that have been connected to neurological disorders.
For more information: Neurobiochemistry
The Groß-Hardt lab explores the molecular basis of plant reproduction. Key research topics focus on cellular life and death decisions, the mechanisms that build and bypass plant polyspermy barriers and the biological significance of mitochondrial diversity. The team capitalizes on state of the art genetic and molecular engineering tools and collaborates with European leaders in plant breeding to bring their findings to application.
For more information: Molecular genetics
The Harder lab studies chemically mediated interactions and processes in plankton communities, namely between microalgae and bacteria. We culture these microorganisms and study their performance, stress resilience, synergy and metabolic fingerprints. The reciprocal chemical exchange between partners is analyzed by instrumental analytical chemistry, including liquid chromatography, mass-spectrometry and nuclear resonance spectroscopy. The knowledge of chemical drivers of species interactions is useful to understand the susceptibility of these interactions and their ecosystem services under future climatic regimes.
For more information: Marine Chemistry
The Kirstein lab studies how molecular chaperones can remodel amyloid proteins whose misfolding and aggregation is causative for neurodegenerative diseases. We use biochemical in vitro techniques to gain mechanistic insight into chaperone activites and use the nematode C. elegans to model human neurodegenerative diseases such as Alzheimer's and Huntington's disease.
For more information: Cell Biology
Andrea Krause is a member of the Reinhold lab. Her research interest is to decode the molecular mechanism responsible for the endophytic interaction of the nitrogen fixing Azoarcus olearicus BH72 with rice. The research topic focuses on the understanding of signal cascades involved in ethanol induced gene regulation in Azoarcus olearicus BH72.
For more information: Molecular plant-bacteria interactions
The aim of the Islet Biology Laboratory headed by Kathrin Maedler is to establish novel therapies for diabetes, directed to regeneration, survival and function of the pancreatic β-cell; from cellular and molecular models to preclinical studies. Towards this goal, we have discovered the Hippo pathway as important regulator of β-cell fate and currently develop RNA-based therapies.
For more information: Islet Biology Laboratory
The Masseck labs studies the function of the neuromodulator serotonin (5-HT). 5-HT is involved in many cognitive functions and dysregulation of 5-HT is associated with the development and manifestation of several diseases, such as anxiety and depression. But still the role of 5-HT in the central nervous system is not well understood. Our lab investigates molecular, cellular and network action of 5-HT by combining optogenetics, electrophysiology, calcium imaging and behavioral studies.
For more information: Synthetic Biology
The Nehls lab investigates inter-kingdom communication requested for the establishment of a symbiotic organ and its functional adaptation to enable nutrient and metabolite exchange using poplar together with certain soil fungi as models. Technically spoken we have two research foci: transport processes and visualization of gene regulation and metabolism.
For more information: Botany
Mario Waespy is a member of the glycobiochemistry group of Prof. Sørge Kelm. His interest focuses on the investigation of the interactions and functions of glycoproteins on a molecular and atomic level by employing several protein biochemical and instrumental analytical methods.
For more information: Glycobiochemistry