Neurobiochemie

The neurobiochemistry group at the CBIB investigates basic metabolic processes of brain cells. We are interested to understand the glucose and glutathione metabolism of the individual types of brain cells, the metabolic interactions that take place between different types of brain cells, the mechanisms involved in the defence of brain cells against oxidative stress and toxins as well as the handling of nanoparticles by brain cells. As model systems for our studies we investigate primary and secondary cell cultures of the four most important brain cell types (neurons, astrocytes, oligodendrocytes, microglial cells). Aim of our studies is to improve the understanding of metabolic processes in brain and to find the molecular basis for disturbances in brain metabolism that have been reported for neurological disorders.