How can we support surgeons by providing them with 3D image information during an operation, so that they know, for instance, where blood vessels are located during a tumor resection? The Creative Unit, composed of scientists from the fields of radiology, computer science, digital media, cognitive systems, and computer graphics, is tackling questions like these. A core challenge is visualizing time-critical 3D information and testing new forms of interaction in the complex operation environment. Live surgical operations demand robust, efficient solutions and visualizations that the operating clinician can perceive and employ immediately. Especially important is that developed systems take operating situations and contexts into account. New methods should be researched that relevant information is automatically delivered to the surgeon at the right point in time.