Our work on animal cells has a strong focus on mouse embryonic fibroblasts. We are interested in the motility and active deformations of these cells and especially in the mechanisms that lead to the various different forms of cellular motion that are based on the polymerization of actin. One of our special interests thereby lies in the widely observed wave-like phenomena. We study the dynamics of cell morphology in great details using advanced methods of digital image processing.
Cellular motion of fibroblast cells
- Biomechanical aspects of actin bundle dynamics, Julia Lange, Erik Bernitt, Hans-Günther Döbereiner, Frontiers in Cell and Developmental Biology 8, 422, 2020
- Fronts and waves of actin polymerization in a bistability based mechanism of circular dorsal ruffels - Erik Bernitt, Hans-Günther Döbereiner, Nir S. Gov, Arik Yochelis, Nature Communications 8, 15863, 2017
- Spatiotemporal Patterns of Noise-Driven Confined Actin Waves in Living Cells - Erik Bernitt, Hans-Günther Döbereiner, Physical Review Letters 118, 048102, 2017