ESR10
ESR10 Interval estimation for dose-finding studies Projektbeginn: 2015 Projektleitung: Prof. Dr. Werner Brannath Forschungsteam: Arsénio Quingue Nhacolo, Björn Bornkamp (Novartis) Förderung: EU Klinischer [...] project is part of EU project "Improving Design, Evaluation and Analysis of early drug development Studies" (IDEAS) (MARIE SKODOWSKA-CURIE ACTIONS, H2020-MSCA-ITN-2014). The literature on adaptive designs [...] their use in late phase clinical trials. In contrast the use of adaptive designs in early phase studies is much less controversially discussed and generally considered less problematic. However, the issue